发明名称 BIPHENYLENE COMPOUNDS
摘要 There are described biphenylene compounds of formula (I) wherein R1 is a C1-C18alkyl, C2-C18alkenyl, C6-C10aryl or C6-C10aryl or C6-C10heteroaryl radical each unsubstituted or mono- or poly-substituted by hydroxy, halogen, C1-C18alkyl, C1-C18alkoxy, amino, C1-C5monoalkylamino or by di-C1-C5alkylamino; C5-C7cycloalkyl or C5-C7cycloalkenyl each unsubstituted or substituted by C1-C5alkyl; -OR'; or NR'R"; R2 is a C1-C18alkyl, C2-C18alkenyl, C6-C10aryl or C6-C10heteroaryl radical each unsubstituted or mono- poly-substituted by hydroxy, hadroxy, C1-C18alkoxy, amino, C1-C5monoalkylamino or by di-C1-C5alkylamino; -OR'; -NR'R"; or R1 and R2 together form a 5- to 7- membered monocyclic carbocyclic or heterocyclic ring; R3 is hydrogen; C1-C6alkyl or C1-C6alkoxy; R' and R" are each independently of the other hydrogen; unsubstituted or mono- or poly-hydroxy-, halo-, C1-C18alkyl-, C1-C18alkoxy-, amino- or quaternary ammonium groupsubstituted C1-C18alkyl, C5-C7cycloalkyl or phenyl; and n is 0 or 1; wherein, when R2 is OR' or NR'R" and n=1, R1 is not simultaneously OR'; or NR'R". The compounds according to the invention are suitable especially as sun protection agents in cosmetic, pharmaceutical and veterinary medicine preparations.
申请公布号 WO03022790(A3) 申请公布日期 2003.09.04
申请号 WO2002EP09627 申请日期 2002.08.29
申请人 CIBA SPECIALTY CHEMICALS HOLDING INC.;WAGNER, BARBARA;HUEGLIN, DIETMAR 发明人 WAGNER, BARBARA;HUEGLIN, DIETMAR
分类号 A61K8/00;A61K8/35;A61K8/37;A61K8/46;A61K8/49;A61Q17/04;C07C45/72;C07C45/74;C07C49/235;C07C49/67;C07C49/683;C07C49/755;C07C49/796;C07C49/813;C07C67/32;C07C67/343;C07C69/618;C07C69/738;C07C315/04;C07C317/44;C07D239/60;C07D239/62;C07D313/04;C07D453/02 主分类号 A61K8/00
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