| 发明名称 |
NITRATE ESTERS AND THEIR USE FOR NEUROLOGICAL CONDITIONS |
| 摘要 |
Aliphatic nitrate esters having a sulfur or phosphorus atom .beta. or .gamma . to a nitrate group and their congeners having efficacy as neuroprotective agents are described. Preferred nitrate esters may be synthesized by nitration of a 3-bromo-1,2-propanediol, and subsequent reaction to yield the desired mono-, di- or tetra-nitrate ester.
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| 申请公布号 |
CA2255824(C) |
申请公布日期 |
2006.01.24 |
| 申请号 |
CA19972255824 |
申请日期 |
1997.05.30 |
| 申请人 |
QUEEN'S UNIVERSITY AT KINGSTON |
发明人 |
BENNETT, BRIAN M.;THATCHER, GREGORY R.J.;JHAMANDAS, KHEM;BOEGMAN, ROLAND J.;REYNOLDS, JAMES N. |
| 分类号 |
C07C203/04;A61K31/00;A61K31/105;A61K31/185;A61K31/21;A61K31/275;A61K31/39;A61K31/66;A61K31/661;A61P25/28;A61P43/00;C07C255/14;C07C323/12;C07C327/28;C07C331/10;C07C381/02;C07D327/02;C07D327/04;C07F9/09;C07F9/40;C07H11/02 |
主分类号 |
C07C203/04 |
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