Implants with absorbable and non-absorbable features for the treatment of female pelvic conditions

摘要

Described are methods, devices, and systems related to implants for the treatment of a female pelvic condition. The implants include absorbable and non-absorbable materials and can be introduced into the pelvic area transvaginally. Meshes of the invention provide benefits relating to improved tissue integration into the mesh, reduced infection likelihood, improved patient comfort following implantation, or combinations of thereof.

主权项

1. An implant configured for transvaginal insertion into a female patient to treat a pelvic disorder, the implant comprising: a first non-absorbable mesh layer, a second absorbable layer comprising an absorbable hydroxyalkanoate polymer, wherein the second absorbable layer is non-porous and prevents migration of cells through the second layer prior to degradation of the second absorbable layer within the female patient, and an absorbable adhesive or protruding member comprising an absorbable polyester that is different than the hydroxyalkanoate polymer, that has a rate of degradation that is faster than the hydroxyalkanoate polymer, and which secures the first layer to the second layer, wherein the absorbable adhesive or the protruding member is formulated to absorb more rapidly in vivo than the second absorbable layer.