| 发明名称 |
NON-HUMAN MAMMAL MODEL OF HUMAN DEGENERATIVE DISORDER, USES THEREOF, AND METHOD OF TREATING HUMAN DEGENERATIVE DISORDER |
| 摘要 |
The present application relates to a non-human mammal model of a human neurodegenerative disorder, methods of producing the non-human mammal model, and methods of using the non-human mammal model to identify agents suitable for treating a neurodegenerative disorder. The present application also relates to methods of treating neurodegenerative disorders and restoring normal brain interstitial potassium levels. |
| 申请公布号 |
US2016317681(A1) |
申请公布日期 |
2016.11.03 |
| 申请号 |
US201514701245 |
申请日期 |
2015.04.30 |
| 申请人 |
GOLDMAN Steven A. |
发明人 |
GOLDMAN Steven A. |
| 分类号 |
A61K49/00;A01K67/027;A61K35/545;A61K35/30;A61K45/06 |
主分类号 |
A61K49/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A non-human mammal model of a human neurodegenerative disorder wherein at least 30% of all of its glial cells in its corpus callosum are human glial cells and/or at least 5% of all of its glial cells in the white matter of its brain and/or brain stem are human neurodegenerative disorder specific glial cells. |
| 地址 |
Webster NY US |
