3,5-DI-TERT-BUTYLSTYRENE DERIVATIVES, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

摘要

A 3,5-di-tert-butylstyrene derivative represented by the general formula (1):

wherein R<1> stands for an acyloxy group represented by R<3>COO (R<3> is a hydrogen atom or an alkyl group with C1 SIMILAR C6), an alkoxyl group of R<4>O (R<4> is an alkyl group with C1 SIMILAR C4), a hydroxyl group, or a hydrogen atom; R<2> stands for

(R<5> is a hydrogen atom or an alkyl group with C1 SIMILAR C3 and X<1> is CH2 or an oxygen atom),


(R<5> and X<1> are each the same as defined above), or

(X<2> is an oxygen or sulfur atom),
and salts of its members capable of forming salts and processes for the preparation, and also a pharmaceutical composition comprising, as an active ingredient, the above compound in association with pharmaceutical excipients.