发明名称 |
PURIFICATION OF BLOOD PLASMA OR SERUM: SELECTIVE REMOVAL OF (VERY) LOW DENSITY LIPOPROTEINS (LDL AND VLDL) |
摘要 |
A process is described for removing low density and very low density lipoproteins from blood plasma or serum and recovering the plasma or serum in a physiologically acceptable form. The method involves in a preferred embodiment passing plasma or serum through a cationic ion exchanger equilibrated with a physiologically acceptable saline solution. The ion exchanger is a water insoluble hydrophilic, water swellable cross-linked regenerated or microgranular cellulose matrix substituted with hydroxy C2-C4 alkyl group. The ion exchanger capacity is provided by sulphate groups substituted with from 2 to 6 meq/g. The take up of low density lipoproteins is enhanced by recycling the plasma through the column. |
申请公布号 |
NZ208241(A) |
申请公布日期 |
1987.09.30 |
申请号 |
NZ19840208241 |
申请日期 |
1984.05.22 |
申请人 |
AYERS, JOHN STEPHEN;HANCOCK, WILLIAM STEPHAN;HARDING, DAVID ROGER KAY |
发明人 |
AYERS, JOHN STEPHEN;HANCOCK, WILLIAM STEPHAN;HARDING, DAVID ROGER KAY |
分类号 |
C07K14/00;A61K35/14;A61K35/16;A61K38/16;A61M1/36;B01J39/04;B01J47/00 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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