发明名称 |
SPLIT INTEINS AND USES THEREOF |
摘要 |
The present invention relates generally to robust split inteins. The split inteins described herein are active over a large temperature range, including temperatures as low as 0° C., over a wide pH range, and in the presence of chaotropic salts. The split inteins also show high tolerance to sequence variability in fused heterologous polypeptides and therefore are useful in protein purification and engineering techniques. |
申请公布号 |
EP2761006(B1) |
申请公布日期 |
2016.12.14 |
申请号 |
EP20120772263 |
申请日期 |
2012.09.28 |
申请人 |
Zera Intein Protein Solutions, S.L. |
发明人 |
PALLISSE BERGWERF, Roser;SCHMIDT, Stefan Robert;MARCO FELIU, Dídac;CARVAJAL VALLEJOS, Patricia Karina |
分类号 |
C12N15/62;C07K14/195;C12N1/21;C12N15/82 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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