主权项 |
1. A nitrogen hexacycle compound of Formula IWherein:
One of X and Y is nitrogen and the other is CR2; One of O1 and Q2 is nitrogen and the other is CR2′, or both of Q1 and Q2 are nitrogen; The bicyclic ADEGZ group is a P2 group; The five member ring of the P2 group is partially saturated or aromatic; The six member ring of the P2 group is aromatic; A, D and E each are independently C or nitrogen, the carbon of C being an sp2 carbon and A additionally may be CR6, the carbon of CR6 being an sp3 carbon; The squiggle bond between D and E is a single bond if one of either of D and E is nitrogen, and the squiggle bond between D and E is a double bond if both of D and E are carbon; The dotted bonds of the five member ring may be single or double bonds depending upon the valence and electon configuration of the bonded atom(s). G and Z are each independently nitrogen, NR3, CR4, C(R5)2, oxygen or sulfur, the carbon of CR4 being an sp2 carbon and the carbon of C(R5)2 being an sp3 carbon, provided that: when one of G and Z is oxygen or sulfur, each of A, D and E is an sp2 carbon; G and Z are not together a combination of oxygen and sulfur and are not both oxygen or both sulfur; when G and Z are both C(R5)2, A is CR6 or N and D and E are both sp2 carbons; when G and Z are both CR4, A is CR6 or N and D and E are both sp2 carbons; R1 is selected from hydrogen, an aliphatic group optionally substituted by a functional group or a functional group; R2, R2′, Rn, R4 and each of R5 are each independently selected from hydrogen, an aliphatic group optionally substituted by a functional group, an optionally substituted aromatic group and a functional group with one of R5 preferably being hydrogen; R3 is hydrogen, an aliphatic group optionally substituted by a functional group and a functional group; R6 is hydrogen or an alkyl group of 1 to 3 carbons; n is 0 or an integer of 1 or 2; Ar is an aryl group optionally substituted by a functional group or an aliphatic group; The number of boronic acid or boronic ester groups bonded anywhere to Formula I is one, the boronic acid and boronic ester groups being specific groups of a functional group. |