发明名称 ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME
摘要 The present invention provides an abietane-type diterpene compound having lipid-lowering activity, a method for preparing same, and use of same. Specifically, the compound has the structure shown in formula I. The definitions of the groups are discussed in the specification. The compound of the present invention has activity of increasing in vivo or in vitro ingestion of low-density lipoprotein, and has a potential to be used as a novel lipid-lowering drug.
申请公布号 WO2016192631(A1) 申请公布日期 2016.12.08
申请号 WO2016CN84358 申请日期 2016.06.01
申请人 SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES 发明人 YE, Yang;WANG, Yiping;YAO, Sheng;ZHAO, Jing;TANG, Chunping;XU, Wenwei;KE, Changqiang;XI, Cong
分类号 C07D493/08;A61K31/366;A61P3/06;C07C43/23;C07C62/32;C07C62/36;C07D303/02;C07D307/77;C07D311/80;C07D317/70;C07D319/14 主分类号 C07D493/08
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