发明名称 |
MODULATION OF REGULATORY T CELL FUNCTION VIA PROTEIN KINASE C-ETA |
摘要 |
Compounds, uses and methods for modulating an immune response are provided. In particular, modulating the interaction of PKC&eegr; with CTLA-4 can modulate an immune response. For example, modulating activity or expression of PKC&eegr;, and/or modulating activity or expression of CTLA-4, can be used to modulate interaction of PKC&eegr; with CTLA-4, thereby modulating an immune response. |
申请公布号 |
EP2992086(A4) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20140791378 |
申请日期 |
2014.04.30 |
申请人 |
La Jolla Institute for Allergy and Immunology |
发明人 |
ALTMAN, Amnon;KONG, Kok-Fai |
分类号 |
C12N5/00;A61K38/00;A61K38/16;C12N5/02;C12N15/11 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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