发明名称 RADIOLABELING OF ADENO ASSOCIATED VIRUS
摘要 Provided herein are systems and methods for radiolabeling of recombinant Adeno-Associated Virus (rAAV) with radioactive iodine. Also provided are methods for in vivo imaging and treatment using the radiolabeled rAAV.
申请公布号 US2017067028(A1) 申请公布日期 2017.03.09
申请号 US201615154647 申请日期 2016.05.13
申请人 Ballon Douglas J.;Crystal Ronald G.;Kaminsky Stephen;Kothari Paresh;De Bishnu;Sondhi Dolan;Vallabhajosula Shankar;Babich John 发明人 Ballon Douglas J.;Crystal Ronald G.;Kaminsky Stephen;Kothari Paresh;De Bishnu;Sondhi Dolan;Vallabhajosula Shankar;Babich John
分类号 C12N7/00;A61K51/12;G01N33/60 主分类号 C12N7/00
代理机构 代理人
主权项 1. A method for producing a recombinant adeno-associated virus (rAAV) labeled with radioactive iodine comprising contacting a composition containing rAAV particles with activated radiolabeled iodine to form a mixture and incubating the mixture at about 4-5° C. for at least 10 minutes.
地址 Gillette NJ US