| 发明名称 |
METHODS AND COMPOSITIONS FOR MITOCHONDRIAL REPLACEMENT THERAPY |
| 摘要 |
The invention features methods, kits, and compositions for mitochondrial replacement in the treatment of disorders arising from mitochondrial dysfunction. The invention also features methods of diagnosing neuropsychiatric (e.g., bipolar disorder) and neurodegenerative disorders based on mitochondrial structural abnormalities. |
| 申请公布号 |
US2017065635(A1) |
申请公布日期 |
2017.03.09 |
| 申请号 |
US201615353347 |
申请日期 |
2016.11.16 |
| 申请人 |
The McLean Hospital Corporation |
发明人 |
CATALDO Anne M.;COHEN Bruce M. |
| 分类号 |
A61K35/12;A61K45/06;A61K9/00 |
主分类号 |
A61K35/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for enhancing cardiac or cardiovascular function in a human subject in need thereof, said method comprising administering to said subject a pharmaceutical composition comprising isolated and substantially pure mitochondria in an amount sufficient to enhance said cardiac or cardiovascular function. |
| 地址 |
Belmont MA US |
