| 发明名称 |
SELF-ASSEMBLING NANOPARTICLE DRUG DELIVERY SYSTEM |
| 摘要 |
A self-assembling nanoparticle drug delivery system for the delivery of drugs including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The self-assembling nanoparticle drug delivery system described herein includes viral capsid proteins, such as Hepatitis B Virus core protein, encapsulating the drug, a lipid bi-layer envelope and targeting or facilitating molecules anchored in the lipid bilayer. A method for construction of the self-assembling nanoparticle drug delivery system is also provided. |
| 申请公布号 |
US2017119689(A1) |
申请公布日期 |
2017.05.04 |
| 申请号 |
US201615183167 |
申请日期 |
2016.06.15 |
| 申请人 |
de los Rios Miguel A.;Oh Kenneth J. |
发明人 |
de los Rios Miguel A.;Oh Kenneth J. |
| 分类号 |
A61K9/51;A61K9/127;C12N7/00 |
主分类号 |
A61K9/51 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A self-assembling nanoparticle drug delivery system comprising:
a capsid comprised of viral capsid proteins; a drug captured in said capsid; and a lipid bi-layer enveloping said capsid. |
| 地址 |
Del Mar CA US |
