| 发明名称 | Method for prevention or treatment of intractable inflammatory bowel disease | ||
| 摘要 | An object of the present invention is to provide methods for preventing or treating a steroid-resistant or steroid-dependent inflammatory bowel disease. The object can be achieved by a method for preventing or treating a steroid-resistant or steroid-dependent inflammatory bowel disease in a patient in need of the prevention or treatment of the inflammatory bowel disease, comprises administering an effective amount of adrenomedullin, a modified product thereof having an activity of suppressing steroid-resistant or steroid-dependent inflammation, or a salt thereof having an activity of suppressing steroid-resistant or steroid-dependent inflammation, to the patient. | ||
| 申请公布号 | US9629895(B2) | 申请公布日期 | 2017.04.25 |
| 申请号 | US201213979048 | 申请日期 | 2012.01.12 |
| 申请人 | University of Miyazaki | 发明人 | Kitamura Kazuo;Ashizuka Shinya;Inatsu Haruhiko;Kita Toshihiro |
| 分类号 | A61K38/17;A61K38/22 | 主分类号 | A61K38/17 |
| 代理机构 | McCarter & English, LLP | 代理人 | McCarter & English, LLP |
| 主权项 | 1. A method for alleviating or suppressing the progress of a steroid-resistant or steroid-dependent inflammatory bowel disease in a patient afflicted with the disease comprising administering to the patient an effective amount of adrenomedullin, a modified product thereof or a salt of the adrenomedullin or the modified product, each of which has an activity of suppressing inflammation in the patient, thereby alleviating or suppressing the progress of the steroid-resistant or steroid-dependent inflammatory bowel disease in the patient, wherein the alleviating or suppressing the progress of the steroid-resistant or steroid-dependent inflammatory bowel disease in the patient comprises mucosal regeneration. | ||
| 地址 | Miyazaki JP | ||