| 发明名称 | 7-deazapurine nucleosides for therapeutic uses | ||
| 摘要 | The invention provides compounds of formula I:; wherein R1, R2 and R3 have values defined in the specification and a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers, as well as compositions comprising such compounds and therapeutic methods that utilize such compounds and/or compositions. | ||
| 申请公布号 | US9624257(B2) | 申请公布日期 | 2017.04.18 |
| 申请号 | US201615073502 | 申请日期 | 2016.03.17 |
| 申请人 | Institute of Organic Chemistry and Biochemistry of the ASCR, V.V.I. | 发明人 | Bourderioux Aurelie;Hocek Michal;Naus Petr |
| 分类号 | C07H19/14;A61K31/7064;A61K45/06 | 主分类号 | C07H19/14 |
| 代理机构 | Kilpatrick Townsend and Stockton, LLP | 代理人 | Kilpatrick Townsend and Stockton, LLP |
| 主权项 | 1. A compound of formula 1: wherein: R1 is hydrogen, mono-, di-, or tri-phosphate; R2 is selected from the group consisting of thiophen-2-yl, thiophen-3-yl, furan-3-yl, and benzofuran-2-yl; R3 is hydrogen; or a pharmaceutically acceptable salt thereof; or an optical isomer thereof; or a mixture of optical isomers. | ||
| 地址 | Prague CZ | ||