发明名称 CONTROLLED RELEASE FORMULATIONS OF LEVODOPA AND USES THEREOF
摘要 The current invention provides a controlled release oral solid formulation of levodopa comprising levodopa, a decarboxylase inhibitor, and a carboxylic acid. Also provided by this invention is multiparticulate, controlled release oral solid formulations of levodopa comprising: i) a controlled release component comprising a mixture of levodopa, a decarboxylase inhibitor and a rate controlling excipient; ii) a carboxylic acid component; and iii) an immediate release component comprising a mixture of levodopa and a decarboxylase inhibitor.
申请公布号 US2017100480(A1) 申请公布日期 2017.04.13
申请号 US201615382851 申请日期 2016.12.19
申请人 Impax Laboratories, Inc. 发明人 Hsu Ann;Kou Jim;Alani Laman
分类号 A61K47/12;A61K9/50;A61K31/198 主分类号 A61K47/12
代理机构 代理人
主权项
地址 Hayward CA US