Macroinitiator containing hydrophobic segment

摘要

The present invention relates to macroinitiators comprising at least one hydrophobic segments in a molecule, wherein a molecular weight of the hydrophobic segment is 300 to 1800. The present invention further relates to block copolymers, wetting agent and polymeric materials having the block copolymers of the present invention associated with, which is suitable for medical devices, particularly for ophthalmic devices, including contact lenses, ophthalmic lenses, punctal plugs and artificial corneas.

主权项

1. A medical device prepared from a mixture comprising a pre-formed silicone hydrogel lens and a block copolymer expressed by formula (b1) or (b2): wherein R1 is selected from the group consisting of an alkyl group or an alkoxy group; R2 is selected from the group consisting (CH2)n and (CH2)m—O(CH2)n; m and n are independent, ranging from 1 to 16; a is from 4 to 19; b is from 1 to 6, c is from 1 to 10,000, X is selected from the group consisting O, NH, and S; and R3 and R4 represent hydrophilic groups that, together with the repeat unit of which they are a part, are the residue from a hydrophilic monomer.