发明名称 MODELING OF PHARMACEUTICAL PROPAGATION AND PARAMETER GENERATION FOR INJECTION PROTOCOLS
摘要 A system includes a parameter generation system to determine at least one parameter for an injection procedure (for example, a parameter of an injection protocol or an imaging system parameter), the parameter generator system includes a physiologically based pharmacokinetic model to model propagation of a contrast medium injected into a patient including at least one of a non-linear saturation term in a peripheral venous compartment, at least one configurable transport delay term through at least one compartment, or an adaptation to model volumetric flow rate of blood and an effect thereof on the propagation of contrast medium after injection of contrast medium ceases. The physiologically based pharmacokinetic model can, for example, be discretizable.
申请公布号 EP2585116(A4) 申请公布日期 2017.03.29
申请号 EP20110798986 申请日期 2011.06.24
申请人 Bayer Healthcare LLC 发明人 KALAFUT, John, F.
分类号 G06F19/00;A61K49/04 主分类号 G06F19/00
代理机构 代理人
主权项
地址