Composites and scaffolds suitable for bone void filling comprising at least a recombinant gelatin and hydroxyapatite in which the recombinant gelatin comprises glutamic and aspartic acid residues that are distributed homogeneously along a gelatin chain, wherein: (i) the recombinant gelatin comprises a total of at least a 8% glutamic and/or aspartic acids amount per 60 amino acids in row with a standard deviation of at most 1.6; (ii) the hydroxyapatite is obtained by precipitation in the presence of the recombinant gelatin.
申请公布号
WO2017048120(A1)
申请公布日期
2017.03.23
申请号
WO2016NL50633
申请日期
2016.09.14
申请人
FUJIFILM MANUFACTURING EUROPE B.V.
发明人
KLUIJTMANS, Sebastianus Gerardus Johannes Maria;VAN DONGEN, Elisabeth Marianna Wilhelmina Maria;PAWELEC, Kendell Marleen;KNYCHALA, Jonathan