| 发明名称 |
POLYNUCLEOTIDE AGENTS TARGETING PATATIN-LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3 (PNPLA3) AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to polynucleotide agents targeting a Patatin-Like Phospholipase Domain Containing 3 (PNPLA3) gene, and methods of using such polynucleotide agents to inhibit expression of a PNPLA3 gene and methods of treating subjects having Nonalcoholic Fatty Liver Disease (NAFLD) and/or a PNPLA3-associated disorder. |
| 申请公布号 |
WO2017048620(A1) |
申请公布日期 |
2017.03.23 |
| 申请号 |
WO2016US51252 |
申请日期 |
2016.09.12 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
HINKLE, Gregory |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
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