ORAL PHARMACEUTICAL DOSAGE FORMS OF BUDESONIDE

摘要

The present invention relates to a sustained release pharmaceutical dosage form for delivery of budesonide to the lower gastrointestinal tract for the treatment of Crohn's disease. Said dosage form comprises (a) an inert core, (b) a first layer composed of sugar and an insoluble polymer (e.g. ethyl cellulose) in a ratio greater than 3:1 and (c) a second delayed film coating, which is preferably an enteric coating.