发明名称 |
METHODS OF MAKING NETUPITANT AND INTERMEDIATES THEREOF |
摘要 |
Methods are disclosed for the preparation of netupitant and pharmaceutically acceptable salts thereof which are novel, easily reproducible, environmentally safe and cost effective. The methods may employ inexpensive starting materials and the preparation processes for intermediates are simple and highly reproducible. Novel intermediates for the preparation of netupitant and pharmaceutically acceptable salts thereof are also disclosed. Amorphous netupitant and methods of making same are disclosed. |
申请公布号 |
EP3140007(A1) |
申请公布日期 |
2017.03.15 |
申请号 |
EP20150789752 |
申请日期 |
2015.05.04 |
申请人 |
Apicore US LLC |
发明人 |
KOVI, Ravishanker;KANNAPAN, Jayaraman;THAKOR, Sanjay F.;NAIK, Ashish |
分类号 |
A61P1/08;C07D213/82;C07D401/04 |
主分类号 |
A61P1/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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