发明名称 USE OF AN ANTI-TAU PS422 ANTIBODY FOR THE TREATMENT OF BRAIN DISEASES
摘要 An antibody binding to Tau that is phosphorylated at serine 422 (pS422), which specifically binds to phosphorylated Tau fragment of SEQ ID NO:9 and to Tau pS422, but does not bind to Tau and to phosphorylated MCAK fragment of SEQ ID NO:17. The antibody is useful in the treatment of a Tauopathy.
申请公布号 EP2440578(B1) 申请公布日期 2017.03.08
申请号 EP20100722962 申请日期 2010.06.08
申请人 F. Hoffmann-La Roche AG 发明人 BOHRMANN, Bernd;GOEPFERT, Ulrich;GRUENINGER, Fiona;HUBER, Walter;KRELL, Hans-Willi;LIFKE, Valeria;MUNDIGL, Olaf;OFFNER, Sonja;OZMEN, Laurence;SCHRAEML, Michael
分类号 C07K16/18;A61K39/395 主分类号 C07K16/18
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