| 主权项 |
1. A method for treating a patient in need of analgesia, the method comprising
determining or receiving the patient's genotype for at least one genetic variant selected from the group consisting of ABCB1 rs9282564, ABCC3 rs4148412, and ABCC3 kgp8560677, assigning the patient into one of two risk groups defined as low and high risk for a serious opioid-induced adverse event, based upon the patient's genotype for the at least one genetic variant, selecting a medication for the patient based upon the patient's assigned risk group, wherein the medication is selected from a non-morphine opioid or a non-opioid analgesic if the patient is assigned to the high risk group and the medication is selected from morphine or another opioid analgesic if the patient is assigned to the low risk group, and administering the non-morphine opioid, non-opioid analgesic, morphine, or other opioid analgesic to the patient in need of analgesia. |
