| 发明名称 |
EBV ANTIGEN SPECIFIC T-CELL RECEPTOR AND USE THEREOF |
| 摘要 |
The present invention relates to an EBV antigen specific T-cell receptor and the use thereof. Specifically, the present invention provides T cells specific for LMP1 of EBV using a T-cell receptor which is highly specific for specific epitopes derived from an EBV antigen, LMP1. In addition, the EBV antigen specific T-cell can be used in the prevention or treatment of EBV-associated diseases. |
| 申请公布号 |
US2017056473(A1) |
申请公布日期 |
2017.03.02 |
| 申请号 |
US201514928762 |
申请日期 |
2015.10.30 |
| 申请人 |
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
KIM Tai Gyu;CHO Hyun Il |
| 分类号 |
A61K38/17;C07K14/705 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A T-cell receptor capable of binding to a peptide derived from a latent membrane protein 1 (LMP1) of an Epstein-Barr Virus (EBV) on being presented by a major histocompatibility complex (MHC), wherein the peptide is represented by an amino acid sequence set forth in SEQ ID NO: 1. |
| 地址 |
Seoul KR |
