| 发明名称 |
TREATMENT OF HYPERBILIRUBINEMIA |
| 摘要 |
The invention relates to a nucleic acid sequence useful in the treatment of hyperbilirubinemia, in particular in the treatment of Crigler-Najjar syndrome. More particularly, the nucleic acid sequence of the present invention is a codon-optimized UGT1A1 coding sequence. |
| 申请公布号 |
EP3134530(A2) |
申请公布日期 |
2017.03.01 |
| 申请号 |
EP20150719677 |
申请日期 |
2015.04.27 |
| 申请人 |
Genethon;I.C.G.E.B. International Centre for Genetic Engineering and Biotechnology |
发明人 |
MINGOZZI, Federico;RONZITTI, Giuseppe;COLLAUD, Fanny;MURO, Andrés;BORTOLUSSI, Giulia |
| 分类号 |
C12N15/86;A61K38/45;A61K48/00;C12N9/10 |
主分类号 |
C12N15/86 |
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