| 摘要 |
PROBLEM TO BE SOLVED: To provide an excipient agglomerated material, production method thereof, and a tablet using the excipient agglomerated material which can inhibit aggregation in spite of long time storage, has high moldability, can be obtained excellent tablet hardness, and further has a low reactivity with the component contained in the tablet.SOLUTION: The invention relates to an excipient agglomerated material and the like which can be obtained by flowing powders containing a disaccharide sugar alcohol in a fluidized bed granulator, and by spraying a disaccharide sugar alcohol to the powders to granulate, and the volume mean particle diameter of the agglomerated material obtained by the granulation is 70 μm-170 μm, and the aggregation rate is 30% or less when the agglomerated material is stored for two weeks under the environment of 40°C, 75% of relative humidity. |
