| 发明名称 |
METHODS FOR THE SYNTHESIS OF FUNCTIONALIZED NUCLEIC ACIDS |
| 摘要 |
Described herein are methods for the synthesis of derivatives of thiosulfonate reagents. Said reagents have utility for the synthesis of phosphorothiotriesters from H-phosphonates in a stereospecific fashion. |
| 申请公布号 |
EP2734208(B1) |
申请公布日期 |
2017.03.01 |
| 申请号 |
EP20120814522 |
申请日期 |
2012.07.13 |
| 申请人 |
Wave Life Sciences Ltd. |
发明人 |
VERDINE, Gregory, L.;MEENA;IWANOTO, Naoki;BUTLER, David, Charles Donnell |
| 分类号 |
C07H13/04;A61K31/66;A61K31/70;C07C309/66;C07D295/108;C07H21/04 |
主分类号 |
C07H13/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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