发明名称 |
Isotopically labeled triazolopyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors |
摘要 |
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds of formula I: or stereoisomers or pharmaceutically acceptable salts thereof, wherein R* is an isotopically labeled hydroxypropyl moiety.; |
申请公布号 |
US9580422(B2) |
申请公布日期 |
2017.02.28 |
申请号 |
US201415031301 |
申请日期 |
2014.10.21 |
申请人 |
Bristol-Myers Squibb Company |
发明人 |
Cheng Yaofeng;Chen Weiqi;Maxwell Brad D.;Tran Bach D.;Li Jun |
分类号 |
A61K31/44;C07D401/00;C07D471/04;C07B59/00;A61K31/437 |
主分类号 |
A61K31/44 |
代理机构 |
|
代理人 |
Korsen Elliott |
主权项 |
1. A compound, enantiomer, diastereomer, or salt thereof, of a compound of formula I: wherein R* is an isotopically labeled hydroxypropyl moiety. |
地址 |
Princeton NJ US |