| 发明名称 |
LIVE-ATTENUATED VACCINE HAVING MUTATIONS IN VIRAL POLYMERASE FOR THE TREATMENT AND PREVENTION OF CANINE INFLUENZA VIRUS |
| 摘要 |
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive. |
| 申请公布号 |
WO2017031404(A1) |
申请公布日期 |
2017.02.23 |
| 申请号 |
WO2016US47715 |
申请日期 |
2016.08.19 |
| 申请人 |
UNIVERSITY OF ROCHESTER;CORNELL UNIVERSITY |
发明人 |
MARTINEZ-SOBRIDO, Luis;NOGALES-GONZALEZ, Aitor;PARRISH, Colin |
| 分类号 |
A61K39/12;A61K39/00 |
主分类号 |
A61K39/12 |
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