OPTIMIZATION OF NUCLEATION AND CRYSTALLIZATION FOR LYOPHILIZATION USING GAP FREEZING
摘要
This application discloses devices, articles, and methods useful for producing lyophilized cakes of solutes. The devices and articles provide for a method of freezing liquid solutions of the solute by the top and the bottom of the solution simultaneously and at approximately the same rate. The as frozen solution can then provide a lyophilized cake of the solutes with large and uniform pores.
申请公布号
EP2831526(B1)
申请公布日期
2017.02.22
申请号
EP20120716817
申请日期
2012.03.28
申请人
Baxter International Inc;Baxter Healthcare SA
发明人
KUU, Wei-Youh;DOTY, Mark, J.;HURST, William, S.;REBBECK, Christine, L.