发明名称 Antibodies against factor XII and uses thereof
摘要 Provided are antibodies that selectively bind to and inhibit activation of coagulation factor XII. Methods of treatment employing these antibodies are described herein.
申请公布号 US9574013(B2) 申请公布日期 2017.02.21
申请号 US201314649972 申请日期 2013.12.06
申请人 VANDERBILT UNIVERSITY;ARONORA, INC.;OREGON HEALTH & SCIENCE UNIVERSITY 发明人 Gruber Andras;Gailani David;Leung Philberta;Matafonov Anton
分类号 A61K39/395;C07K16/36;C07K16/40;A61K39/00 主分类号 A61K39/395
代理机构 Parker Highlander, PLLC 代理人 Parker Highlander, PLLC
主权项 1. An antibody which binds factor XII comprising: (a) a light chain comprising light chain CDRs represented by SEQ ID NOS: 1, 2 and 3; and (b) a heavy chain comprising heavy chain CDRs represented by SEQ ID NOS: 4, 5 and 6.
地址 Nashville TN US