发明名称 |
Amphiphilic compounds with neuroprotective properties |
摘要 |
The present invention provides amphiphilic compounds with tetradecahydrophenanthrene skeleton and their enantiomers, exhibiting neuroprotective effects, their use as medicaments for treating neuropsychiatric disorders associated with an imbalance in glutamatergic neurotransmitter system, such as ischemic damage of CNS, neurodegenerative changes and disorders of CNS, affective disorders, depression, post-traumatic stress disorder and diseases related to stress, anxiety, schizophrenia and psychotic disorders, pain, addiction, multiple sclerosis, epilepsy, glioma, and a pharmaceutical composition containing said compound. |
申请公布号 |
AU2015309371(A1) |
申请公布日期 |
2017.02.16 |
申请号 |
AU20150309371 |
申请日期 |
2015.08.25 |
申请人 |
Ustav Organicke Chemie A Biochemie Av Cr, V.v.i.;Fyziologicky Ustav Av Cr, V.v.i. |
发明人 |
Kudova, Eva;Chodounska, Hana;Kapras, Vojtech;Vyklicky, Ladislav;Vales, Karel;Jahn, Ullrich |
分类号 |
C07J1/00;A61K31/56;A61P25/00;A61P25/08;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;C07C13/60;C07C55/00;C07C211/63;C07C279/14;C07C305/20;C07J9/00;C07J13/00;C07J31/00;C07J41/00;C07J43/00;C07J63/00;C07J71/00 |
主分类号 |
C07J1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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