发明名称 |
METHOD OF SCREENING CANDIDATE BIOCHEMICAL ENTITIES TARGETING A TARGET BIOCHEMICAL ENTITY |
摘要 |
Described herein are methods useful for screening candidate biochemical entities targeting a target biochemical entity and methods useful for identifying a binding moiety for a target biochemical entity. The invention provides methods of screening drug candidates targeting a target biomolecule, comprising selecting a drug candidate based on a signal difference between a first signal and a second signal. The signal difference indicates a difference in an in vivo or in vitro pharmacological property. The first signal is produced upon binding between the target biomolecule and a first candidate by contacting the target biomolecule with the first candidate, and the second signal is produced upon binding between the target biomolecule and a second candidate by contacting the target biomolecule with the second candidate. |
申请公布号 |
EP3008465(A4) |
申请公布日期 |
2017.02.15 |
申请号 |
EP20140810249 |
申请日期 |
2014.06.13 |
申请人 |
Biodesy, Inc. |
发明人 |
SALAFSKY, Joshua;MOREE III, Carl, Benton |
分类号 |
G01N33/487;G01N33/68 |
主分类号 |
G01N33/487 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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