发明名称 CYCLOPROPANAMINE COMPOUND AND USE THEREOF
摘要 The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
申请公布号 EP3129369(A1) 申请公布日期 2017.02.15
申请号 EP20150721046 申请日期 2015.04.09
申请人 Takeda Pharmaceutical Company Limited 发明人 MATSUMOTO, Shigemitsu;HATTORI, Yasushi;TOYOFUKU, Masashi;MORIMOTO, Shinji;DAINI, Masaki;KOJIMA, Takuto;KAKU, Tomohiro;ITO, Mitsuhiro
分类号 C07D413/14;A61K31/166;A61K31/421;C07D213/82;C07D231/14;C07D285/08;C07D285/135;C07D333/38;C07D333/40;C07D407/12;C07D409/12;C07D417/12;C07D417/14 主分类号 C07D413/14
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