ACOUSTIC AFFINITY SEPARATION

摘要

Methods and systems for separating a first biomaterial from a second biomaterial can use functionalized material retained in a liquid-filled chamber at locales within an acoustic standing wave field. A culture suspension containing the first biomaterial and the second biomaterial flows into the liquid-filled chamber and at least portions of the first biomaterial with features complementary to the functionalized material becomes bound to the functionalized material while other portions of the culture suspension containing the second material pass through the chamber. The portion of the first biomaterial bound to the functionalized material is subsequently released from the liquid filled chamber.