| 发明名称 |
GENETICALLY ENGINEERED POLYMER LIBRARIES AND METHODS OF USING THEM |
| 摘要 |
Disclosed herein are methods of identifying polymers having particular biological or physical characteristics from in vivo generated libraries of polymers. Methods of generating in vivo polymer libraries are also described. Polymers identified using the methods of the invention are also described. |
| 申请公布号 |
US2017029812(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201515115212 |
申请日期 |
2015.01.28 |
| 申请人 |
LOS ALAMOS NATIONAL SECURITY, LLC |
发明人 |
Martinez Jennifer S.;Close Devin W.;Lillo Antonietta M.;Murdock Balog Eva Rose;Kiss Csaba;Rocha Reginaldo C.;Bradbury Andrew R.M.;Ghosh Koushik;Sista Prakash;Wang Hsing-Lin;Strauss Charlie E. |
| 分类号 |
C12N15/10;C07K7/06;C07K1/04;C07K7/08 |
主分类号 |
C12N15/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of identifying a polymer comprising:
subjecting a plurality of first display systems to a selective pressure, wherein the first display systems contain at least one polymer exposed on the surface thereof; isolating at least one first display system that contains at least one polymer that responds to a selective pressure; isolating the DNA encoding the at least one polymer that responds to the selective pressure; and identifying the polymer that responds to the selective pressure. |
| 地址 |
Los Alamos NM US |
