Methods and materials for assessing homologous recombination deficiency
摘要
This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of homologous recombination deficiency (HRD) or an HRD signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an HRD signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
申请公布号
AU2015301390(A1)
申请公布日期
2017.02.02
申请号
AU20150301390
申请日期
2015.08.17
申请人
Reid, Julia;Timms, Kirsten;Gutin, Alexander;Abkevich, Victor;Myriad Genetics, Inc.
发明人
Abkevich, Victor;Timms, Kirsten;Gutin, Alexander;Reid, Julia