发明名称 METHOD FOR PRODUCING 2-ACETYL-4H,9H-NAPHTHO[2,3-B]FURAN-4,9-DIONE
摘要 The invention addresses the problem of providing a method for producing 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione that is suited to industrial production. The invention provides a method for producing 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione by reacting 3-bromo-3-buten-2-one and 2-hydroxy-1,4-naphthoquinone in the presence of a solvent, then obtaining crystals of 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione by adding an alcohol-based solvent and/or water to the reaction system, and treating the crystals by using a specific adsorbent in the presence of a solvent.
申请公布号 WO2017013865(A1) 申请公布日期 2017.01.26
申请号 WO2016JP03346 申请日期 2016.07.15
申请人 SUMITOMO DAINIPPON PHARMA CO., LTD. 发明人 YAGI, Toshikazu;SUZUKI, Satoshi;TATAMIDANI, Hiroto;HASHIMOTO, Kazuki
分类号 C07D307/92;A61K31/343;C07C45/65;C07C49/227 主分类号 C07D307/92
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