发明名称 |
METHOD FOR PRODUCING 2-ACETYL-4H,9H-NAPHTHO[2,3-B]FURAN-4,9-DIONE |
摘要 |
The invention addresses the problem of providing a method for producing 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione that is suited to industrial production. The invention provides a method for producing 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione by reacting 3-bromo-3-buten-2-one and 2-hydroxy-1,4-naphthoquinone in the presence of a solvent, then obtaining crystals of 2-acetyl-4H,9H-naphtho[2,3-b]furan-4,9-dione by adding an alcohol-based solvent and/or water to the reaction system, and treating the crystals by using a specific adsorbent in the presence of a solvent. |
申请公布号 |
WO2017013865(A1) |
申请公布日期 |
2017.01.26 |
申请号 |
WO2016JP03346 |
申请日期 |
2016.07.15 |
申请人 |
SUMITOMO DAINIPPON PHARMA CO., LTD. |
发明人 |
YAGI, Toshikazu;SUZUKI, Satoshi;TATAMIDANI, Hiroto;HASHIMOTO, Kazuki |
分类号 |
C07D307/92;A61K31/343;C07C45/65;C07C49/227 |
主分类号 |
C07D307/92 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|