发明名称 |
COQ10 (UBIQUINONE, UBIQUINOL), VITAMIN A (RETINOIC ACID, RETINOL), VITAMIN E (TOCOTRIENOL, TOCOPHEROL) AND METHODS OF USE |
摘要 |
CoQ10 and vitamin E are both lipid-soluble nutrients with redox potential. Tocopherol and/or tocotrienol protect CoQ10 from oxidative damage and reduce ubiquinone in situ. Specifically, vitamin E protects the oxidation of ubiquinol to ubiquinone ex vivo and reduces ubiquinone to ubiquinol in situ. Vitamin Es with higher ratio of tocotrienol-to-tocopherol cause a higher ratio of ubiquinol-to-ubiquinone. Additionally tocopherol and/or tocotrienol protect vitamin A oxidation from retinol to retinoic acid. |
申请公布号 |
EP3016644(A4) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20140819403 |
申请日期 |
2014.07.03 |
申请人 |
Tan, Barrie |
发明人 |
Tan, Barrie |
分类号 |
A61K31/122;A61K9/06;A61K31/05;A61K31/07;A61K31/352;A61K31/353;A61K31/355;A61K31/593;A61K36/899;A61K47/24 |
主分类号 |
A61K31/122 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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