| 发明名称 | Compositions and methods for diagnosis and treatment of hepatic cancers | ||
| 摘要 | The present invention relates to methods of treating liver cancer using a Notch signaling inhibitor. Compositions and methods for the treatment of liver cancers are also provided. | ||
| 申请公布号 | US9550829(B2) | 申请公布日期 | 2017.01.24 |
| 申请号 | US201414208523 | 申请日期 | 2014.03.13 |
| 申请人 | Genentech, Inc. | 发明人 | French Dorothy;Huntzicker Erik;Siebel Christian W. |
| 分类号 | A61K39/395;C07K16/18;C07K16/22;C07K16/30;C07K16/28;A61K47/48;C07K14/475;C07K14/52;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | McNeill Baur PLLC | 代理人 | McNeill Baur PLLC |
| 主权项 | 1. A method of treating a liver cancer in an individual in need thereof, comprising administering to the individual an effective amount of an anti-Jagged1 (anti-Jag1) antibody, wherein the liver cancer comprises cells that express EpCAM. | ||
| 地址 | South San Francisco CA US | ||