| 发明名称 |
NASAL VACCINE FOR STREPTOCOCCUS PNEUMONIAE |
| 摘要 |
The present invention provides a nasal vaccine for Streptococcus pneumoniae, and a production method therefor. This nasal vaccine formulation for primates includes a complex of PspA, i.e. the vaccine antigen, and a nanogel in which hydrophobic cholesterol is added, as side chains, to pullulan having amino groups. Furthermore, the present invention provides a production method for the nasal vaccine formulation for primates. |
| 申请公布号 |
US2017014338(A1) |
申请公布日期 |
2017.01.19 |
| 申请号 |
US201515119335 |
申请日期 |
2015.02.16 |
| 申请人 |
LSIP, LLC |
发明人 |
YUKI Yoshikazu;KIYONO Hiroshi;AKIYOSHI Kazunari;SAWADA Shinichi |
| 分类号 |
A61K9/00;A61K47/36;A61K39/09 |
主分类号 |
A61K9/00 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A nasal vaccine formulation for primates, comprising a complex of a nanogel in which hydrophobic cholesterol is added, as side chains, to pullulan having an amino group, and PspA serving as a vaccine antigen, the nanogel having the amino group added at a ratio of 18 to 22 per 100 glucose units. |
| 地址 |
Tokyo JP |
