发明名称 |
TRPM4 CHANNEL INHIBITORS FOR STROKE TREATMENT |
摘要 |
The present invention relates to methods for treating ischemic stroke including extension of the therapeutic time window for reperfusion. More particularly, the invention relates to a method of treating stroke in a subject by inhibiting the transient receptor potential melastatin 4 (TRPM4) channel. The present invention also provides uses of TRPM4 inhibitors, TRPM4 antibodies and kits for use in the methods of the invention. |
申请公布号 |
EP3013857(A4) |
申请公布日期 |
2017.01.18 |
申请号 |
EP20140818531 |
申请日期 |
2014.06.30 |
申请人 |
Singapore Health Services Pte Ltd |
发明人 |
LIAO, Ping;LOH, Kok Poh |
分类号 |
C07K16/18;A61K31/713;A61K39/00;A61K39/395;A61K45/06;A61P25/00;C07K16/28;C12N15/113 |
主分类号 |
C07K16/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|