发明名称 |
TRANSMUCOSAL DELIVERY OF LAQUINIMOD BY ORAL PATCHES |
摘要 |
The subject invention provides an oral patch comprising: a) a liner; and b) a film composition thereon, the film composition comprising (i) laquinimod in an amount of about 0.1%-20% by weight of the film composition, and (ii) one or more film forming agents in a total amount of about 40%-90% by weight of the film composition. The subject invention also provides a method for delivering laquinimod across the oral mucosa of a subject, or for treating a human subject afflicted with a form of multiple sclerosis, comprising periodically administering to the human subject an oral patch as described herein. The subject invention also provides an oral patch as described herein for use in treating a human subject afflicted with a form of multiple sclerosis. |
申请公布号 |
EP3116554(A1) |
申请公布日期 |
2017.01.18 |
申请号 |
EP20150762375 |
申请日期 |
2015.03.13 |
申请人 |
Teva Pharmaceutical Industries Ltd. |
发明人 |
STEFAN, Ralph;MIKA, Hans, Juergen;LAUER, Claudia;SCHENK, Dirk;PROHL, Sabine |
分类号 |
A61L15/44 |
主分类号 |
A61L15/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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