发明名称 Salts of an epidermal growth factor receptor kinase inhibitor
摘要 The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same.
申请公布号 US9540335(B2) 申请公布日期 2017.01.10
申请号 US201514822366 申请日期 2015.08.10
申请人 Celgene Avilomics Research, Inc. 发明人 Lai Mei;Witowski Steven Richard;Tester Richland Wayne;Lee Kwangho
分类号 C07D239/48 主分类号 C07D239/48
代理机构 Choate, Hall and Stewart LLP 代理人 Choate, Hall and Stewart LLP ;Buteau Kristen C.
主权项 1. Compound 2: wherein: n is 1 or 2; andX is hydrobromic acid, benzenesulfonic acid, camphor sulfonic acid, 1,2-ethane disulfonic acid, hydrochloric acid, maleic acid, methanesulfonic acid, naphthalene-2-sulfonic acid, 1,5-naphthalene disulfonic acid, oxalic acid, 4-toluenesulfonic acid or 2,4,6-trihydroxybenzoic acid.
地址 Cambridge MA US