发明名称 |
Salts of an epidermal growth factor receptor kinase inhibitor |
摘要 |
The present invention provides a salt form and compositions thereof, which are useful as an inhibitor of EGFR kinases and which exhibits desirable characteristics for the same. |
申请公布号 |
US9540335(B2) |
申请公布日期 |
2017.01.10 |
申请号 |
US201514822366 |
申请日期 |
2015.08.10 |
申请人 |
Celgene Avilomics Research, Inc. |
发明人 |
Lai Mei;Witowski Steven Richard;Tester Richland Wayne;Lee Kwangho |
分类号 |
C07D239/48 |
主分类号 |
C07D239/48 |
代理机构 |
Choate, Hall and Stewart LLP |
代理人 |
Choate, Hall and Stewart LLP ;Buteau Kristen C. |
主权项 |
1. Compound 2: wherein:
n is 1 or 2; andX is hydrobromic acid, benzenesulfonic acid, camphor sulfonic acid, 1,2-ethane disulfonic acid, hydrochloric acid, maleic acid, methanesulfonic acid, naphthalene-2-sulfonic acid, 1,5-naphthalene disulfonic acid, oxalic acid, 4-toluenesulfonic acid or 2,4,6-trihydroxybenzoic acid. |
地址 |
Cambridge MA US |