发明名称 Fiber wadding for filling bone defects
摘要 A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 μm to about 30 μm. Bulk density of the fiber wadding is about 0.005-0.3 g/cm3.
申请公布号 US9539365(B2) 申请公布日期 2017.01.10
申请号 US201414495649 申请日期 2014.09.24
申请人 Orthorebirth Co. Ltd.;Nagoya Institute of Technology 发明人 Kasuga Toshihiro;Obata Akiko;Fujikura Kie;Ota Yoshio;Yao Xianfeng
分类号 A61F2/28;C08K9/02;A61L27/32;A61L27/44;A61L27/18;A61L27/26;A61K9/70;A61K31/755;A61K31/80;A61K33/10;A61L24/02;A61L24/04;A61L27/54;A61L27/58;A61F2/30;A61F2/44 主分类号 A61F2/28
代理机构 Osha Liang LLP 代理人 Osha Liang LLP
主权项 1. A fiber wadding for filling bone defects, comprising: a plurality of biodegradable fibers produced by using an electrospinning apparatus having a collector filled with ethanol, wherein electrospun fibers emitted from a nozzle of the electrospinning apparatus enter into the ethanol of the collector, and the fiber sink in the ethanol and are deposited in the collector, wherein the plurality of biodegradable fibers are entangled with each other to form a flocculent three dimensional structure having a bulk density from about 0.01 g/cm3 to about 0.1 g/cm 3, as measured in accordance with JIS L 1097, wherein the plurality of biodegradable fibers comprise a biodegradable resin and a Si-releasable calcium compound.
地址 Kanagawa JP