发明名称 |
METHODS FOR THE SITE-SELECTIVE COUPLING OF A FIRST AGENT TO A SECOND AGENT |
摘要 |
The present invention relates to a method for site-selective coupling of a first agent to a second agent, comprising the steps of: contacting a first agent comprising at least one furan moiety with an activation signal and with a second agent comprising at least one hydrazine moiety or at least one hydroxylamine moiety, thereby activating said furan moiety to an activated furan moiety; and reacting said activated furan moiety with the hydrazine moiety or the hydroxylamine moiety, thereby site-selectively coupling said first agent to said second agent. |
申请公布号 |
WO2017001204(A1) |
申请公布日期 |
2017.01.05 |
申请号 |
WO2016EP63854 |
申请日期 |
2016.06.16 |
申请人 |
UNIVERSITEIT GENT |
发明人 |
MADDER, Annemieke;ANTONATOU, Eirini;HOOGEWIJS, Kurt |
分类号 |
C07K1/13;C07K1/107 |
主分类号 |
C07K1/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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