发明名称 |
Ambient Infrared Laser Ablation Mass Spectrometry (AIRLAB-MS) with Plume Capture by Continuous Flow Solvent Probe |
摘要 |
A new experimental setup for spatially resolved ambient infrared laser ablation mass spectrometry (AIRLAB-MS) that uses an infrared microscope with an infinity-corrected reflective objective and a continuous flow solvent probe coupled to a Fourier transform ion cyclotron resonance mass spectrometer is described. The efficiency of material transfer from the sample to the electrospray ionization emitter was determined using glycerol/methanol droplets containing 1 mM nicotine and is ˜50%. This transfer efficiency is significantly higher than values reported for similar techniques. |
申请公布号 |
US2017004959(A1) |
申请公布日期 |
2017.01.05 |
申请号 |
US201514740176 |
申请日期 |
2015.06.15 |
申请人 |
O'Brien Jeremy T.;Williams Evan R.;Holman Hoi-Ying N. |
发明人 |
O'Brien Jeremy T.;Williams Evan R.;Holman Hoi-Ying N. |
分类号 |
H01J49/04;H01J49/16 |
主分类号 |
H01J49/04 |
代理机构 |
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代理人 |
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主权项 |
1. A system for spatially resolved ambient infrared laser ablation mass spectrometry (AIRLAB-MS) comprising an infrared microscope with an infinity-corrected reflective objective, an infrared laser, a continuous flow solvent probe coupled to a mass spectrometer having an electrospray ionization emitter, and a stage for the sample to be subjected to laser ablation mass spectrometry. |
地址 |
Cambridge MA US |