TIME, SPACE DIGITALLY RESOLVED QUANTIFICATION OF LUMINESCENT TARGETS

摘要

A sensor device (100) for quantifying luminescent targets. The device comprises a light source (111) for exciting the targets, thus generating luminescence signals, and a detector (120) for detecting these signals of the targets in a cell (310), resulting in a detected signal comprising a desired signal and a background signal. The detector (120) has a spatial cell resolution and/or a time resolution that is so high that only a limited number of targets will be present in the cell when measuring at low concentration and/or that only a limited number of targets add to the cell in between two measurements. A change in the number of targets in the cell can be observed in the detected signal. The device comprises a processor (140) configured to distinguish the desired and the background signal, and to combine the detected signals of the different cells and/or moments in time, to quantify the targets.