COMPOSITION DERIVED FROM STEM CELL RELEASED MOLECULES & METHODS FOR FORMULATION THEREOF

摘要

Compositions for use in treatment of a variety of tissue diseases include stem cells and stem cell released molecules (SRM's) suspended in an aqueous solution with a cellulosic material or other thickening agent. The stem cells and SRM's can be derived from one or more distinct cell lines. The SRM's can further include one or more mucins, cytokines, or growth factors. Exemplary formulations include stem cells and SRMs derived from epithelial stem cells, corneal limbal stem cells, and fibroblasts. Other compositions and methods for formulation thereof are described.

主权项

1. A therapeutic composition for hair growth treatment, comprising:
an amount of stem cells and stem cell released molecules derived from a first cell line collectively defining a first adjuvant material, wherein said first cell line comprises one of: mesenchymal stem cells, epithelial stem cells, limbal stem cells, or fibroblasts; an amount of stem cells and stem cell released molecules derived from a second cell line and a third cell line collectively defining a second adjuvant material, wherein said second or third cell line each comprises one of: mesenchymal stem cells, epithelial stem cells, limbal stem cells, or fibroblasts, and wherein each of said second cell line said third cell line is distinct from said first cell line; and a thickening agent comprising at least one of a cellulosic material or a polymer; said first adjuvant material, second adjuvant material, and thickening agent being combined in an aqueous solution.